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Design, fabrication and biomedical applications of zein-based nano/micro-carrier systems.  
Design, fabrication and biomedical applications of zein-based nano/micro-carrier systems.
资料类型: PDF文件
关键词: Biopolymer  Nano/microparticle  Nanocapsule  Microcapsule  Delivery  carrier  
资料大小: 580k
所属学科: 通用高分子材料
来源: 来源网络
简介:
Nano/micro-carrier systems have shown promising application in the biomedicalfield as various deliverycarriers. The composite material and fabrication method determine their microstructures, properties andthus their potential applications. Since approved as tablet coating material by the U.S. Food and DrugAdministration (US-FDA), zein has been widely investigated as one of protein-based materials in the pastfew decades. Zein is renewable, biodegradable and relatively inexpensive in comparison with animalproteins (e.g., gelatin and albumin). This paper reviews the current landscape of zein-based nano/micro-carrier systems, with particular emphasis on nano/microparticles, nano/microcapsules and their design,fabrication, assembly mechanisms and biomedical applications especially for controlled drug delivery.The benefits, challenges and related solutions of zein-based colloidal carrier systems are also discussed.In addition, investigations on the molecular structure, biocompatibility and immunogenicity of zein aresummarized and discussed.
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