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Multifunctional 3D Au@ MOF Nanocomposite Array as a Platform for Biomarkers Detection  
Multifunctional 3D Au@ MOF Nanocomposite Array as a Platform for Biomarkers Detection
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关键词: early  cancer  detection  plasmonic  .  SERS  Au  
MOF  
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简介:
Lungcancer(LC)istheleadingcauseofcancermortality,withmorethanImilliondeathsworldwideeveryyear.Earlyandaccuratedetectionofcancerpermitseffectiveintervention,whichfacilitatesefficacioustherapyandmonitoringoftherapeuticprogression.andcanreducemortalityandmorbidity.However,conventionaldiagnosticmethods,suchaschestX-ray,computedtomography(CT),magneticresonanceimaging(MRI),andpositronemissiontomography(PET)[l],areunsuitableforwidespreadscreeningbecausetheyaretime-consuming,expensive,and.furthermore,occasionallymisstumours.Additionally,thetechnologiesassociatedwiththeseapproachesareunavailableinmanymedicalfacilitiesandrequirerelativelylargeamountsoftissueforanalysis.Thedevelopmentofnewpoint-of-carediagnosticstrategieswithsufficientsensitivityandspecificityforearlycancerdetectionisalwaysbeingsoughtfordiseasediagnosisandseveritygrading.
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