摘要：本发明属于高分子材料领域，尤其涉及一种改性SEBS材料及其制备方法和应用，该材料包括：多巴胺修饰的SEBS和两个端基均接枝在所述SEBS表面的亲水聚合物；所述亲水聚合物的两个端基选自巯基、氨基、羧基或磺酸基。本发明以多巴胺作为仿生粘合剂，将亲水聚合物的两端固定到SEBS表面，构建了亲水聚合物的loop构象，表面接枝全过程无有机溶剂的使用，避免了有机溶剂的污染和毒害。本发明通过在SEBS表面构建loop构象的亲水聚合物，较在SEBS表面构建brush构象的亲水聚合物进一步提升了SEBS材料抵抗蛋白质和血小板粘附的能力，表现出优异的血液相容性，将其应用于生物医用材料领域能产生良好的社会经济效益。

Abstract:The present invention belongs to the field of polymer materials, and particularly relates to a modified SEBS material as well as its preparation method and application. The material comprises dopamine-modified SEBS and hydrophilic polymers with both terminal groups grafted onto the surface of the SEBS. The two terminal groups of the hydrophilic polymer are selected from thiol groups, amino groups, carboxyl groups or sulfonic acid groups.In the present invention, dopamine is used as a bio-adhesive to immobilize both ends of the hydrophilic polymer on the SEBS surface, forming a loop conformation of the hydrophilic polymer. No organic solvents are adopted in the entire surface grafting process, thus eliminating pollution and toxic hazards caused by organic solvents.Compared with SEBS grafted with hydrophilic polymers in brush conformation, the SEBS material constructed with loop-conformation hydrophilic polymers in this invention exhibits further enhanced resistance to protein and platelet adhesion, and delivers outstanding blood compatibility. When applied in the field of biomedical materials, the material can bring favorable social and economic benefits.