[Sensors and Actuators B]A Reversible Fluorescent Probe for Zn2+and ATP in Living Cells and in Vivo
writer：X. L. Jin, X. L. Wu, B. Wang, P. Xie, Y. L. He, H. W. Zhou,*B.Yan,J.J.Yang,W.X.Chen,X. H. Zhang*
keywords：Fluorescein,Zinc ion,ATP,Visualizing,Fluorescence
source：期刊
specific source：Sensors and Actuators B, 2018, 261, 127-134.
Issue time：2018年
A reversible fluorescein-based fluorescent probe which exhibits high sensitivity and selectivity for Zn2+ and ATP, has been designed and synthesized. The sensing process was completed via fluorescence variation induced by an opening and closing of the spiro-ring of fluorescein. Zn2+/ATP-induced fluorescent intensity shows a good linear relationship with the concentration of Zn2+/ATP in the range of 0–10 μM with a detection limit of 0.1 μM/0.5 μM. Moreover, the probe was further applied to visualize and detect Zn2+and ATP in vitro and in vivo.