The Nano-Biotechnology Lab is created by Group leader Dr. Xiangyang Shi in 2008, June and affiliated with the College of Chemistry, Chemical Engineering, and Biotechnology at the Donhua University. We specialize in the Nanomedicine, Environmental Nanotechnology, Nanochemistry and Nanomaterials Synthesis. The research interests are as following:
1. Dendrimer surface-modification and conjugation, dendrimer-based nanodevices for targeted drug delivery; synthesis and self-assembly of dendrimer-metal nanocomposite materials and their application in environmental and medical sciences; surface modification and conjugation of dendrimer-metal nanocomposite particles with dyes, targeting moieties, and drugs for cell labeling markers, targeting, and therapeutic applications; biofunctionalization of magnetic nanoparticles for medical imaging and therapeutic applications.
2. Fabrication of high-ordered organic and inorganic hybrid nanomaterials, organic or inorganic nanotubes, nanowires, core-shell particles, hollow spheres, nanoengineering of particle surfaces, and biofunctionalization of nanoparticles; designation and fabrication of biocapsules to encapsulate and release bioactive materials for biomedical applications, e.g. encapsulation and release of biomolecular or organic microcrystals in polymer multilayer cages; synthesis of porous nanocomposite thin films, nanoassemblies of biomolecular, organic, and inorganic hybrid materials and their properties and applications in catalysis, biocatalysis, biosensing, etc.
3. Development of capillary electrophoresis and HPLC methods for the analysis of various dendrimeric nanostructures: functional dendrimers, dendrimer-metal nanocomposites, and multifunctional dendrimer nanodevices.
4. Developing nanofiber-based technology with an emphasis on the synthesis and fabrication of bioscaffolding materials in tissue engineering applications and the immobilization of reactive nanoparticles within nanofibrous mats for environmental applications.