writer：Guodu Liu, Kexuan Huang, Chaoxian Cai, Bonan Cao, Mingxin Chang, Wenjun Wu,* Xumu Zhang.*
keywords：regioselective Hydroaminomethylation
source：期刊
specific source：Chem-Eur. J. 2011, 17, 14559-14563. (DOI: 10.1002/chem.201103073, full paper, IF = 5.160, Citation:
Issue time：2011年

A highly regioselective hydroaminomethylation of terminal olefins catalyzed by Rh complexes with 2, 2′, 6, 6′‐tetrakis ((diphenylphosphino)methyl)‐1, 1′‐biphenyl (Tetrabi) ligand has been 

developed. Up to 99?% amine selectivity, 168 linear/branched amine product ratio (n/i), and 97.4?% linear amine yield has been obtained at a substrate/rhodium precursor ratio (S/Rh) of 1000 with this methodology. The turnover number was achieved 6930 at 10000 S/Rh ratio,

and the n/i can reach up to >525. Several different olefins and secondary amines have been applied successfully with high chemoselectivity (99?%), yield (>98?%), and regioselectivity 

(>120).