Dual functional coatings with anti-fog and antimicrobial performances greatly enhance the safety and reliability of medical detection devices, but are prone to mechanical damage, resulting in reduced performance and a shorter service lifespan. Herein, a semi-interpenetrating polymer network (SIPN) coating, featuring hydrophobichydrophilic balanced copolymers as bulk chains and host–guest inclusion compounds (HGICs) as cross-linkers, is

reported, which demonstrates particularly effective anti-fog and antibacterial performances, along with a surprisingly fast self-healing capability under various scenarios. This HGIC-based coating displayed remarkable antifog capability over a wide temperature range from ?? 20 ℃ to 85 ℃ and exhibited reliable antibacterial activities (≥98 %) against both gram-positive and gram-negative bacteria. Also, this coating showed extremely high selfhealing ability (≥92 % recovery rate) within just 20 s, significantly outperforming traditional self-healing systems.

These findings support the development of functional coatings that can highly maintain rapid self-healing performance while also providing anti-fog and antibacterial properties in medical detection devices.