搜索: 产品 厂商 新闻 资料 资源

岛津网络讲堂《Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy》即将开讲

公司:岛津企业管理(中国)有限公司/岛津(香港)有限公司   日期:2018-11-08




SPONSORED BY: Shimadzu

C.E. CREDITS: P.A.C.E. CE | Florida CE

REGISTER NOW

Speakers




Atsuhiko (Ash) Toyama, PhD

MS Application Specialist, Analytical & Measuring Instruments Division, Shimadzu Corporation

Biography

Ash Toyama has 10 years of proteomics research experience. His areas of expertise include not only proteomics but also quantitative mass spectrometry with particular focus on bioanalysis, metabolomics and endocrinology. At Shimadzu Corporation he played roles in academic research collaborations, application development and specification development of mass spectrometers. Ash holds a Master of Science degree in Biochemistry from University of Cambridge, UK, and was granted a Ph.D. degree in Biological Sciences from University of Tokyo for his research on clinical proteomics.



Abstract:

High-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matrix and to allow identification of compounds by measuring their accurate masses. In particular, those coupled to liquid chromatograph (HRAM LC/MS) have been used extensively for structural elucidation of unknown compounds primarily in chemical industry (impurity analysis) and biological researches (proteomics, metabolomics, lipidomics), but also increasingly in forensic science, food safety and environmental testing. Given the recent reduction of instrumentational cost, it will not take many more years until HRAM analysis becomes a versatile tool for all industries and researches. 

The key performance attribute underlying all application fields is mass measurement accuracy (MMA) as it affords molecular specificity and reduction of false positive results. MMA is given in the specification of HRAM instruments in parts-per-million (ppm), frequently stating a result of a set of representative measurements e.g. “<1 ppm RMS”. However, this by itself does not convey how repeatably and reproducibly this MMA can be achieved. 

The webinar describes various metrics that are relevant to statistical interpretation of MMA, which explain why mass resolution of 30,000 is more than sufficient for mass measurement at sub-ppm accuracy. Using the Shimadzu LCMS-9030 quadrupole time-of-flight MS, the rationale and strength of instrument stability for consistently achieving sub-ppm MMA has been demonstrated in small molecules.

Learning objectives:













 

关于岛津

    岛津企业管理(中国)有限公司是(株)岛津制作所于1999100%出资,在中国设立的现地法人公司,在中国全境拥有13个分公司,事业规模不断扩大。其下设有北京、上海、广州、沈阳、成都分析中心,并拥有覆盖全国30个省的销售代理商网络以及60多个技术服务站,已构筑起为广大用户提供良好服务的完整体系。本公司为了人类和地球的健康为经营理念,始终致力于为用户提供更加先进的产品和更加满意的服务,为中国社会的进步贡献力量。

·
《石木高分子板材应用技术标准》启动会暨战...
·
Carbon宣布降低环氧树脂和聚氨酯3D打印树...
·
海胶集团携手中国航发航材院共同成立特种天...
·
全球塑料助剂行业发展概况及竞争格局分析
·
普立万一款TPE材料,能降低80%的电器振动
·
赢创开发出第一种3D打印用人体植入级别PEE...
最新资讯
·
《石木高分子板材应用技术标准》启动会暨战...
·
第二十二届全国玻璃钢复合材料学术交流会
·
Carbon宣布降低环氧树脂和聚氨酯3D打印树...
·
中华人民共和国政府和加拿大政府关于应对海...
·
美国温哥华企业呼吁公众支持研发绿色塑料包...
·
SABIC 沙特基础工业公司推出LEXAN? CXT...
·
英国:超跑汽车公司开发石墨烯增强碳纤维复...
·
海胶集团携手中国航发航材院共同成立特种天...
·
全球塑料助剂行业发展概况及竞争格局分析
·
墨西哥采取措施提高塑料工业的可持续性
·
SONGWON 产业集团发布 2018 年第三季度财...
·
以技术革新推进产品创新