作者：X. L. Jin, X. L. Wu, B. Wang, P. Xie, Y. L. He, H. W. Zhou,*B.Yan,J.J.Yang,W.X.Chen,X. H. Zhang*
关键字：Fluorescein,Zinc ion,ATP,Visualizing,Fluorescence
论文来源：期刊
具体来源：Sensors and Actuators B, 2018, 261, 127-134.
发表时间：2018年

A reversible fluorescein-based fluorescent probe which exhibits high sensitivity and selectivity for Zn²⁺ and ATP, has been designed and synthesized. The sensing process was completed via fluorescence variation induced by an opening and closing of the spiro-ring of fluorescein. Zn²⁺/ATP-induced fluorescent intensity shows a good linear relationship with the concentration of Zn²⁺/ATP in the range of 0–10 μM with a detection limit of 0.1 μM/0.5 μM. Moreover, the probe was further applied to visualize and detect Zn²⁺and ATP in vitro and in vivo.