作者：Shujin Wang, Ziting Liu, Li Wang, Jianing Xu, Ru Mo,* Yue Jiang,* Cuie Wen, Zhihui Zhang, and Luquan Ren
关键字：bacterial repellency,；mechano-bactericidal； multifunctional surface,；photodynamic antibacterial,；superhydrophobicity
论文来源：期刊
具体来源：ACS Publications
发表时间：2022年

Bacterial invasion and proliferation on various surfaces pose a serious threat to public health worldwide. Conventional antibacterial strategies that mainly rely on bactericides exhibit high bacteria-killing efficiency but might trigger the well-known risk of antibiotic resistance. Here, we report a superhydrophobic mechano-bactericidal surface with photodynamically enhanced antibacterial capability. First, bioinspired nanopillars with polycarbonate as the bulk material were replicated from anodized alumina oxide templates via a simple hot-pressing molding method. Subsequently, a facile bovine serum albumin phase-transition method was used to introduce chlorin e6 onto the nanopillar-patterned surface, which was then perfluorinated to

render the surface superhydrophobic. Benefiting from its strong liquid super-repellency and photodynamically enhanced mechano-bactericidal properties, the superhydrophobic nanopillar-patterned surface exhibits 100% antibacterial efficiency after 30 min visible light irradiation (650 nm, 20 mW cm?2 ). More strikingly, the surface exhibited impressive long-lasting antimicrobial performance, maintaining a very high bactericidal efficiency (≥99%) even after 10 cycles of bacterial contamination tests. Also, the superhydrophobic nanopillar-patterned surface displays good hemocompatibility with a much lower than the 5% hemolysis rate. Overall, this work offers a new method for significantly enhancing the antibacterial efficiency of structural antimicrobial surfaces without involving any bactericidal agents, and this functional surface shows great potential in the field of advanced medical materials and hospital surfaces.