作者：Jie Gao, Lingwan Hao, Rujian Jiang, Zhuo Liu, Limei Tian, Jie Zhao, Weihua Mingd and Luquan Ren
关键字：none
论文来源：期刊
具体来源：Green Chemistry
发表时间：2022年

Antibacterial surfaces that provide synergetic photothermal/photodynamic therapy (PTT/PDT) offffer apromising avenue for combating bacterial infections but generally require a time-consuming and cumbersome chemical preparation procedure. Herein, a metal–organic framework (MOF) composite fifilm withPTT/PDT antibacterial performance is realized through a surprisingly fast and sustainable chelationinduced self-assembly between ZIF-8 particles and dopamine (DA). Unlike traditional DA polymerization,usually in an alkaline medium with a long reaction time (e.g. more than 20 h), a robust and universal MOF composite fifilm with DA as the linker can be rapidly assembled within only 0.5 h on various bulk materials under neutral (pH = 7) conditions. The resultant MOF fifilm is extremely robust, and can even withstand harsh ultrasonic cleaning (150 W, 50 kHz, 10 min) and maintain its intact nanostructure. After being incorporated with indocyanine green (ICG), the obtained composite fifilms achieved effiffifficient synergetic PTT/ PDT against both Gram-positive and -negative bacteria under single NIR irradiation (808 nm). This PTT/ PDT antibacterial fifilm also exhibited excellent in vitro biocompatibility, thus revealing the great potential for medical antibacterial surface applications.