writer：Liangjing Fang, Sujing Chen, Ying Zhang, Huiqi Zhang*
keywords：Molecularly imprinted polymers, azobenzene, photoresponsive, binding properties
source：期刊
specific source：J Mater Chem 2011, 21(7), 2320-2329.
Issue time：2011年
The first successful preparation of azobenzene (azo)-containing molecularly imprinted polymer (MIP) microspheres with photoresponsive template binding properties is described. A methacrylate azo functional monomer with a pyridine group was used for this purpose, and its good solubility in acetonitrile allowed the implementation of molecular imprinting via precipitation polymerization, leading to azo-containing MIP microspheres (number-average diameter = 1.33 mu m, polydispersity index = 1.15) with obvious molecular imprinting effects towards the template 2,4-dichlorophenoxyacetic acid (2,4-D), rather fast template rebinding kinetics, and appreciable selectivity over structurally related compounds. The binding association constant K-a and apparent maximum number N-max for high-affinity sites of the imprinted polymer in the dark environment were determined by Scatchard analysis to be 2.3 x 10(4) M-1 and 10.0 mu mol g(-1), respectively. Most importantly, the binding affinity of the imprinted sites in azo-containing MIP microspheres was found to be photoresponsive towards the template, which decreased upon UV light irradiation (as revealed by the resulting lower K-a value for high-affinity sites and reduced specific bindings), whereas it could be recovered during the subsequent thermal (or visible light-induced) back-isomerization. Furthermore, this photoregulation process proved to be highly repeatable under photoswitching conditions.