作者：Yun-Pu Wang, Fa-Ai Zhang, Hai-Tao Zhang and Yu-Feng Li
关键字：Transition metal polypyridyl complexes, Synthesis, Characterization, DNA, Interaction
论文来源：期刊
具体来源：Journal of bioactive and compatible polymers
发表时间：2010年

Five water-soluble polymer-supported transition metal polypyridyl complexes were synthesized from polyacrylic acid -co- N-vinyl pyrrolidone, 2-methyl-3-hydroxyl benzaldehyde, o-phenanthroline and metal acetate salts. Infrared spectra (IR), thermo-gravimetric and differential thermal analysis (TG-DTA), Inductance Coupling Plasma (ICP) and X-ray photoelectron spectroscopy (XPS) measurement technologies were used to characterize their composites and structures. Their interaction with DNA was studied according to fluorescent probe method and gel electrophoresis method. The results indicated that these complexes had strong interaction with DNA, there may exist other rupture mode of DNA.