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课题组工作在Synthesis上发表

摘要:

Efficient and divergent one-pot synthesis of cyclopropyl amides and esters from readily available 1-acetylcyclopropanes via iodoform reaction based on reaction conditions selection is reported. A series of substituted cyclopropyl amides were synthesized from 1-acetyl-cyclopropanes in the presence of iodine and ammonia in water in good yields, whereas substituted cyclopropyl esters were obtained from the reaction of 1-acetylcyclopropanes with iodine and alcohols in the presence of DBU.