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[JOC] Hydrogen Bond-Assisted 6π-Azaelectrocyclization of Penta-2,4-dienamides: Synthesis of Dihydropyridin-2(3H)-ones
writer:Xu Liu, Ning Zhang, Jiming Yang, Yongjiu Liang, Rui Zhang, and Dewen Dong
keywords:electrocyclization, dihydropyridin
source:期刊
specific source:J. Org. Chem.
Issue time:2013年

A facile and efficient synthesis of substituted dihydropyridin-2(3H)-ones is developed from penta-2,4-dienamides, in which an intramolecular C–N bond was formed through thermal 6π-azaelectrocyclization. The intramolecular hydrogen bonding-assisted cyclization reaction opens access to a variety of dihydropyridin-2(3H)-ones.