A fluorescent probe for benzenethiols and its application on test paper, in water samples and living cells
writer:Zhang, W. Y.; Liu, X. J.; Zhang, H. Y.; Feng, C. C.; Liu, C. X.; Yu, M. M.; Wei, L. H.; Li, Z.
keywords:SELECTIVE DETECTION; SENSITIVE DETECTION; AROMATIC THIOLS; GLUTATHIONE; THIOPHENOLS; CYSTEINE; NAPHTHALIMIDE; EMISSION; CHEMODOSIMETER; HOMOCYSTEINE
source:期刊
specific source:J. Mater. Chem. C, 2015, 3, 8248–8254
Issue time:2015年
It is important to develop probes for rapid, selective, and sensitive detection of highly toxic benzenethiols in both environmental and biological science. In this work, based on the selective cleavage reaction by benzenethiols under mild conditions, a novel naphthalimide-based fluorescent probe was designed and synthesized for the rapid recognition of benzenethiols with excellent selectivity and anti-interference over other various species including some nucleophilic species, aliphatic thiols, anions and metal ions. The limit of quantification (LOQ) value was 0-4.0 mu M and the detection limit could be as low as 10.3 nM. The fluorescence enhancement of this probe upon addition of benzenethiol on test paper and the application of the probe for selective detection in water samples and living cells have been successfully demonstrated.