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β-Cyclodextrin-based polymeric nano-receptor: the self-assembly of cyclodextrin-appended comb-copolymer
writer:Yan Kang, Jinying Yuan*, Qiang Yan, Liyao Zheng, and Lilin Zhou
keywords:cyclodextrin; self-assembly; nano-receptors; comb-copolymer
source:期刊
specific source:Polymers for Advanced Technologies, DOI: 10.1002/pat.1863
Issue time:2011年

Well-defined b-cyclodextrin (b-CD)-appended biocompatible comb-copolymer ethyl cellulose-graft-poly (e-caprolactone) (EC-g-PCL) was synthesized via the combination of ring-opening polymerization (ROP) and click chemistry. The resulting products were characterized by 1H NMR, FT-IR spectroscopy, and GPC. The synthesized comb-copolymer could assemble to micelles, with the surface covered by b-CD. The inclusion with ferrocene derivation was investigated by cyclic voltammetric (CV) experiments, which indicated the potential application of the micelles as nano-receptors for molecule recognization and controlled drug release.