writer：Yi Yan, Weiwen Zhao, Ganga Viswanathan Bhagavathy, Alexandre Faurie, Nicholas
keywords：macrocycle, stimulus-responsive, ion-binding
source：期刊
specific source：Chem. Commun.2012, 48, 7829-7831.
Issue time：2012年

The partial positive charge of amide protons is used to promote macrocyclization and form crown-ether analogs. Their deprotonation generates very selective pH-switchable alkaline earth ion receptors only in the presence of an appropriate substrate.