writer：Rong Min Wang, Juan Juan Mao, Jing Feng Song, Cai Xia Huo, Yu Feng He
keywords：Natural polymer; Schiff-base metal complexes; Glutamic acid; Bovine serum albumin (BSA); Antioxidants; Hydroxyl radicals
source：期刊
specific source：Chinese Chemical Letters 18 (2007) 1416–1418
Issue time：2007年

Glutamic acid–salicylaldehyde Schiff-base metal complexes are bound into bovine serum albumin (BSA), which afforded BSA binding Schiff-base metal complexes (BSA-SalGluM, M Cu, Co, Ni, Zn). The BSA binding metal complexes were characterized by UV–vis spectra and Native PAGE. It showed that the protein structures of BSA kept after coordinating amino acid Schiff-bases metal complexes. The effect of the antioxidant activity was investigated. The results indicate that the antioxidant capacity of BSA increased more than 10 times after binding Schiff-base metal complexes.