作者：Zhao Liu, Ziqing Tang, Lin Zhu* and Qiang Chen*, et al.
关键字：hydrogels; natural protein, high strength
论文来源：期刊
具体来源：International Journal of Biological Macromolecules
发表时间：2019年

Natural protein-based hydrogels with high strength and rapid self-recovery

Zhao Liu#,Ziqing Tang#,Lin Zhu*,Shaoping Lu,Feng Chen,Cheng Tang,Huan Sun,Jia Yang,Gang Qin,Qiang Chen*

International Journal of Biological Macromolecules,Volume 141, 1 December 2019, Pages 108-116

https://doi.org/10.1016/j.ijbiomac.2019.08.258

Natural protein hydrogels are considered as the promising candidates for biomaterials. However, natural protein hydrogels often exhibit poor mechanical properties. Herein, using bovine serum albumin (BSA) as natural protein model, a new kind of D/C-hybrid DN gels, consisting of tetrakis(hydroxymethyl)phosphonium chloride (THPC) cross-linked BSA (THPC-BSA) as dynamic covalent bond cross-linked first network and covalently cross-linked polyacrylamide (PAAm) as second network, were successfully synthesized by a facile method. Different from fully chemical DN gels without recovery, the optimized THPC-BSA/PAAm D/C-hybrid DN gel not only demonstrated excellent tensile properties, but also displayed extremely fast self-recovery property and fatigue resistance. More importantly, various natural proteins could be also used to prepare natural protein-based D/C-hybrid DN gels, and all of them showed improved mechanical properties and fast self-recovery properties. The results indicate our new strategy to fabricate recoverable natural protein-based D/C-hybrid DN gels is general. We hope our new strategy as well as our natural protein-based D/C-hybrid DN gels will provide a new avenue to prepare and study high performance natural protein hydrogels.