Abstract:

Polypropylene (PP) non-woven has been widely used as wound dressing; however, the hydrophobicnature of PP can initiate bacterial attachment and subsequent biofilm formation. Herein, we proposea facile approach to functionalize PP non-woven with poly(ethylene glycol) (PEG) and poly(N-vinylpyrrolidone)-iodine complex (PVP-I). PVP and PEG were successively tethered onto PP non-woven surfacevia versatile bioinspired dopamine (DA) chemistry, followed by complexing iodine with PVP moieties.It was demonstrated through the field emission scanning electron microscope (SEM) and spread platemethod that the as-modified PP non-woven integrated both antifouling property of PEG for suppressingbacterial adhesion, and bactericidal property of PVP-I for killing the few adherent bacteria. Meanwhile,it could greatly resist platelet and red blood cell adhesion. The integrated antifouling and bactericidal PPnon-woven surfaces might have great potential in various wound dressing applications.