作者：Xinsong Li, Jingjing Wang, et al.
关键字：Silicone hydrogels; Interpenetrating polymer network; Hybrid photopolymerization; HEMA
论文来源：期刊
具体来源：Biomedical Engineering: Applications, Basis and Communications,2011, 23(2), 153–162
发表时间：2011年

Silicone hydrogels with interpenetrating network (IPN) structure were prepared by ultraviolet (UV)- initiated simultaneous free-radical/cationic polymerizations in order to develop contact lens with high performances. The polymerization mechanism was investigated by gel fracion method using polymerization
of 2-hydroxyethyl methacrylate (HEMA) and 4-hydroxybutyl vinyl ether (HBVE) as a model. The results showed that HEMA and crosslinker ethylene glycol dimethacrylate (EGDMA) polymerized by free-radical mechanism, while HBVE and crosslinker triethylene glycol divinyl ether (DVE-3) polymerized by cationic mechanism. The IPN silicone hydrogels were then prepared by UV-initiated hybrid photopolymerization of monomers including HEMA and bitelechelic polydimethylsiloxane bearing vinyl ethers end-groups (VS) in the presence of free-radical and cationic photoinitiators. Physiochemical properties such as optical properties, ion permeability, contact angle, and mechanical properties of the silicone hydrogels were characterized by UV spectroscopy, ionoflux technique, and tensile tester. The results revealed that the water content, surface wettability, and ion permeability of the hydrogels increased, but the tensile strength and Young’s modulus decreased with the increase of the HEMA content.