作者：Nianzuo Yu, Shuli Wang, Yongshun Liu, Peihong Xue, Peng Ge, Jingjie Nan, Shunsheng Ye, Wendong L
关键字：none
论文来源：期刊
具体来源：Langmuir
发表时间：2017年

We show morphology-patterned stripes modi-

?ed by thermal-responsive polymer for smartly guiding ?ow

motion of ?uid in chips. With a two-step modi?cation process,

we fabricated PNIPAAm-modi?ed Si stripes on silicon slides,

which were employed as substrates for ?uid manipulation in

microchannels. When the system temperature switches

between above and below the lower critical solution

temperature (LCST) of PNIPAAm, the wettability of the

substrates also switches between strong anisotropy and weak

anisotropy, which resulted in anisotropic (even unidirectional)

?ow and isotropic ?ow behavior of liquid in microchannels.

The thermal-responsive ?ow motion of ?uid in the chip is

in?uenced by the applied pressure, the thickness of PNIPAAm, and dimension of the microchannels. Moreover, we measured the

feasible applied pressure scopes under di?erent structure factors. Because of the excellent reversibility and quick switching speed,

the chip could be used as a thermal-responsive microvalve. Through tuning the system temperature and adding the assistant gas,

we realized successive “valve” function. We believe that the practical and simple chip could be widely utilized in medical

detection, immunodetection, protein analysis, and cell cultures.