writer：Ke Ma, Hui Wang, Haolong Li, Shan Wang, Xing Li, Bin Xu?, Wenjing Tian
keywords：ATP detection, AIE, DNA aptasensor, Water-soluble carbon nanotubes
source：其他
specific source：Sensors and Actuators B: Chemical 2016, 230, 556-558.
Issue time：2016年

A label-free and turn-on fluorescent ATP detection is reported with a ss-DNA aptamer as the recognition part, an AIE molecule as the fluorescent probe, and water-soluble carbon nanotubes as the selective part with the fluorescent quenching effect. The specific binding between the aptamer and target ATP makes the aptamer released from the water-soluble carbon nanotubes. As a consequence, the AIE-active probes, attaching on the surface of ss-DNA, recover to give fluorescence and present a strong emission. The introduction of water-soluble carbon nanotubes allows creating low background fluorescence, which is a great advantage for ATP detection.

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