writer：Zhong Luo, Kaiyong Cai, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Peng Liu
keywords：mesoporous silica
source：期刊
specific source：Advanced Materials, 2012, 24, 431–435
Issue time：2012年

A novel redox responsive controlleddrug release system based on magnetic nanoparticles for efficient intracellular anticancer drug delivery is fabricated. Disulfide bonds are employed as intermediate linkers to immobilize PEI/β-CD molecules as nanoreservoirs for drug loading onto magnetic nanoparticles. The endocytotic pathway and endosomal escape of the smart controlled drug release system is proposed.