writer：Peng Liu, Yashao Chen
keywords：polyvinyl chloride; plasma; surface sulfonation; antithrombogenicity
source：期刊
specific source：PLASMA SCIENCE & TECHNOLOGY 卷: 6 期: 3 页: 2328-2332 出版年: JUN 2004
Issue time：2004年

To enhance the blood compatibility of Polyvinyl Chloride (PVC) film, the film was modified by SO(2)/O(2) gas plasma treatment. The effect of surface sulfonation of PVC treated by various SO(2)/O(2) gas plasma depended on the volume ratio O(2)/(SO(2) + O(2)). When the volume ratio was 0.5, the effect of sulfonation was the best. Sulfonic acid groups were specifically and efficiently introduced onto the PVC surface, which was proved by X-ray photoelectron spectroscopy (XPS) and Attenuated Total Reflectance Fourier Transfer Infrared (ATR-FTIR) spectroscopy. The surface microstructure of modified PVC film was studied with scanning electron microscopy (SEM). The antithrombogenicity of the samples was determined by the activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and plasma recalcification time (PRT) tests and platelet adhesion experiment. The results indicated that the antithrombogenicity of modified PVC was improved remarkably.