黄世文：男，博士，武汉大学化学与分子科学学院教授、博士生导师。生物医用高分子材料教育部重点实验室副主任。1989年毕业于南京大学化学系，获学士学位；1992年于武汉大学化学系获硕士学位，留校从事教学科研工作。2002年于武汉大学化学与分子科学学院获理学博士学位。2000年8月－2002年2月公派赴新加坡Johns Hopkins Singapore Biomedical Center进行合作研究。2005年被聘为武汉大学教授、博士生导师。2008年入选教育部新世纪优秀人才支持计划。目前主要研究方向为生物医用高分子材料，包括药物控释、基因载体、纳米生物材料等。在Advanced Materials, Biomaterials, Small, Bioconjugate Chemistry, Biomacromolecules, Polymer, Macromolecular Bioscience等期刊发表论文40余篇，他人正面引用300次，先后获湖北省自然科学一等奖、二等奖各一次。
目前主持的主要项目
1.国家重大科学研究计划
课题一：增溶与促透性纳米给药系统的构建与表征
2.国家自然科学基金
多功能性聚阳离子胶束基因载体研究
2009年1月-2011年12月
3.教育部新世纪优秀人才支持计划
2009年1月2011年12月
近年发表的主要论文：
1. Peng L, Gao Y, Xue YN, Huang SW*, Zhuo RX*. Cytotoxicity and in vivo tissue compatibility of poly(amidoamine) with pendant amino butyl group as a gene delivery vector. Biomaterials, 2010, 31, 4467-4476.
2. Xue YN, Liu M, Peng L, Huang SW*, Zhuo RX. Improving gene delivery efficiency of bioreducible poly(amidoamine)s via grafting with dendritic poly(amidoamine)s. Macromolecular Bioscience, 2010, in press. (doi:10.1002/mabi.200900300).
3. Liu M, Chen J, Cheng Y P, Xue YN, Zhuo RX, Huang SW*. Novel Poly(amidoamine)s with Pendant Primary Amines as Highly Efficient Gene Delivery Vectors. Macromolecular Bioscience, 2010, in press. (doi:10.1002/mabi.200900265).
4. Peng L, Liu M, Xue YN, Huang SW*, Zhuo RX*. Transfection and intracellular trafficking characteristics for poly(amidoamine)s with pendant primary amine in the delivery of plasmid DNA to bone marrow stromal cells. Biomaterials, 2009, 30(29), 5825-5833.
5. Liu M, Chen J, Xue YN, Liu WM, Zhuo RX, Huang S W*. Poly(beta-aminoester)s with Pendant Primary Amines for Efficient Gene Delivery. Bioconjugate Chemistry, 2009, 20(12), 2317-2323.
6. Zhang M, Liu M, Xue YN, Huang SW*, Zhuo RX*. Polyaspartamide-Based Oligo-ethylenimine Brushes with High Buffer Capacity and Low Cytotoxicity for Highly Efficient Gene Delivery. Bioconjugate Chemistry, 2009, 20 (3), 440-446.
7. Xue YN, Huang ZZ, Zhang JT, Liu M, Zhang M, Huang SW*, ZHuo RX*. Synthesis and self-assembly of amphiphilic poly(acrylic acid-b-DL-lactide) to form micelles for pH-responsive drug delivery. Polymer, 2009, 50(15), 3706-3713.
8. Huang SW*, Zhuo RX. Recent advances in polyphosphoester and polyphosphoramidate-based biomaterials. Phosphorus Sulfur and Silicon and The Related Elements, 2008, 183 (2-3), 340-348.
9. Zhang JT*, Xue YN, Gao FZ, Huang SW*, Zhuo RX. Preparation of temperature-sensitive poly(N-isopropylacrylamide)/ -cyclodextrin-grafted polyethylenimine hydrogels for drug delivery. Journal of Applied Polymer Science, 2008, 108, 3031-3037.
10. Chen J, Xia XM, Huang SW*, Zhuo RX*. A cleavable-polycation template method for the fabrication of non-crosslinked and porous polyelectrolyte multilayered films. Advanced Materials, 2007, 19, 979.
11. Chen J, Huang SW*, Lin WH, Zhuo RX*. Tunable Film Degradation and Sustained Release of Plasmid DNAfromCleavable Polycation/Plasmid DNA Multilayeres under Reductive Conditions. Small, 2007, 3，636.
12. Chen J, Huang SW*, Liu M, Zhuo RX*, Synthesis and degradation of poly(beta-aminoester) with pendant primary amine. Polymer, 2007, 48(3), 675.
13. Zhang J T, Huang S W, Xue Y N, Zhuo R X. Poly(N-isopropylacrylamide) nanoparticle- incorporated PNIPAAm hydrogels with fast shrinking kinetics. Macromolecular Rapid Communication, 2005, 26, 1346-1350.
14. Zhang J T, Huang S W, Zhuo R X. A novel sol–gel strategy to prepare temperature-sensitive hydrogel for encapsulation of protein. Colloid Polymer Science, 2005, 284,209-213.
15. Zhang J T, Huang S W, Xue Y N, Zhuo R X. Novel Thermal-Sensitive beta-Cyclodextrin-Contained Poly(N-isopropylacrylamide) Hydrogels Cross-linked by Si-O-Si Bonds: Synthesis, Characterization and Prolonging in Vitro Release of 5-Fluorouracil. Chinese Journal of polymer Science, 2005, 23(5), 513-519.
16. Zhang J T, Huang S W, Liu J, Zhuo R X. Temperature Sensitive Poly[N-isopropylacrylamide-co- (acryloyl b-cyclodextrin)] for Improved Drug Release. Macromolecular Bioscience, 2005, 5, 192-196.
17. Zhang JT, Huang SW, Gao FZ, Zhuo RX. Novel temperature-sensitive,β-cyclodextrin-incorporated poly(N-isopropylacrylamide) hydrogels for slow release of drug. Colloid Polymer Science, 2005,283,461-464
18. Zhang XQ, Wang XL, Huang SW, Zhuo RX Liu ZL,In, Mao HQ, Leong KW. Vitro Gene Delivery Using PAMAM Dendrimers with Trimesyl Core. Biomacromolecules, 2005, 6, 341-350.
19. Zhang J T, Huang S W, Wang L L, Zhuo R X. Preparation and Characteristic of Fast-Responsive, Porous Poly(N-isopropylacylamide-co-Acryl Acid) Hydrogels. Chemical Journal of Chinese University，2004，25(12), 2370-2374.
20. Zhang J T, Huang S W , Zhuo RX. Preparation of temperature-sensitive, polyamidoamine dendrimer-incorporated poly(N-isopropylacrylamide) hydrogels with improved responsive properties. Macromolecular Bioscience, 2004, 2004, 4(6), 575-578.
21. Huang S W, Wang J, Zhang P C, Mao H Q, Zhuo R X, Leong K W. Water-soluble and Nonionic Polyphosphoester: Synthesis, Degradation, Biocompatibility and Enhancement of Gene Expression in Mouse Muscle. Biomacromolecules, 2004, 5(2), 306-311.
22. Wu X Y, Huang S W, Zhang J T, Zhuo R X. Preparation and Characterization of Novel Physically Cross-linkedHydrogels Composed of Poly (vinyl alcohol) and Amine-terminated Polyamidoamine Dendrimer. Macromolecular Bioscience, 2004, 4, 71-75.
23. Zhang J T, Huang S W, Zhuo R X. Preparation and Characterization of Novel Temperature Sensitive Poly(N-isopropylacrylamide-co-acryloyl beta-cyclodextrin) Hydrogels with Fast Shrinking Kinetics. Macromolecular Chemistry and Physics, 2004, 205, 107-113.
24. Zhang J T, Huang S W, Cheng S X, Zhuo R X. Synthesis and Characteristics of Poly(N-isopropylacrylamide)/Poly(N-isopropylacrylamide) Interpenetrating Polymer Network as Drug Delivery System. Journal of Polymer Science, Part A, 2004, 42, 1249-1254.
25. Wu X Y, Huang S W, Zhang J T, Zhuo R X. Preparation and Properties of Physically cross-linked Poly (vinyl alcohol)/ Hydroxy-terminated Polyamidoamine Dendrimer Hydrogels. Chemical Journal of Chinese University, 2004, 25(2), 382-384.
26. Wang J, Huang S W, Zhang P C, Mao H Q, Leong KW. Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. International Journal of Pharmaceutics, 2003, 265(1-2), 75-84.
27. Huang S W, Zhuo R X. Recent progress in polymer-based gene delivery vectors. Chinese Science Bulletin, 2003, 48(13), 1304-1309.
28. Huang S W, Fu L Z, Zhang X Q, Liu H, Li W X, Zhuo R X. Syntheses of polyamidoamine dendrimers starting from a hexadimensional core and application in gene transfer. Science in China Series B, 2003, 46(3), 271-279.
29. Zhang J T, Cheng S X, Huang S W and Zhuo R X. Temperature-sensitive poly(isopropylarylamide) hydrogel with macroporous structure and fast responsive rate. Macromolecular Rapid Communication, 2003, 24(7), 447-451.