writer：Huang SW*, Zhuo RX
keywords：Biomaterial, review
source：期刊
specific source：Phosphorus Sulfur and Silicon and The Related Elements, 2008, 183 (2-3), 340-348
Issue time：2008年

Polyphosphoesters and polyphosphoramidates are important two classes of phosphorous-containing polymers, which have received more and more attention in the past decade for the application in biomedical field. The unique characteristic of biodegradation, biocompatibility and structure versatility of polyphosphoesters and polyphosphoramidates makes it possible to develop a variety of novel phosphate-based polymers for drug delivery, gene delivery and tissue engineering. In this review, we highlighted the recent advances in polyphosphoester and polyphosphoramidate-based biomaterials including synthesis and characterization, degradation, biocompatibility, and important application in drug delivery, gene delivery and nerve repairing.