Multi-stimuli-sensitive polymeric drug carriers are widely investigated for their potential biomedical applications. On page 43026 (1 of 9), Xiangxiang Du, Guohua Jiang, Lei Li, Wentong Yang, Hua Chen, Yongkun Liu and Qin Huang propose a general protocol for the preparation of glucose-sensitive and fluorescence micelles for the controlled release of insulin via a one-pot method that combines photoinitiated polymerization and chemenzymatic tranesterification. The cover image is a fluorescence microscope image of the micelles under blue light irradiation. (DOI: 10.1002/app.43026)