writer：Xiaohong Wang, Guohua Jiang*, Zhen Wei, Xia Li, Bolin Tang
keywords：miniemulsion RAFT polymerization; CO?2 stimulus-sensitive; nanoparticles; drug release.
source：期刊
specific source：European Polymer Journal
Issue time：2013年

The CO₂ stimulus-sensitive nanoparticles based on poly (N, N-dimethylaminoethyl methacrylate)-b-poly styrene (PDMAEMA-b-PS) were prepared via surfactant-free miniemulsion reversible addition-fragmentation chain transfer (RAFT) polymerization. The as-prepared nanoaprticles exhibited core-shell structure with about 120 nm in diameter. Their dispersion/aggregation in water can be adjusted by alternatively bubbling of CO₂ and N₂. Drug release from these nanoparticles can be accelerated (or delayed) by bubbling (or removing) of CO₂.