[Chem. Commun.] A new avenue to the synthesis of GAG-mimicking polymers highly promoting neural differentiation of embryonic stem cells
writer:Wang, MM; Lyu, ZL; Chen, GJ; Wang, HW ;Yuan, YQ;Ding, KG; Yu, Q;Yuan, L;Chen, H
keywords:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC06944K#!divAbstract
source:期刊
specific source:Chem. Commun., 2015,51, 15434-15437
Issue time:2015年
A new strategy for the fabrication of glycosaminoglycan (GAG) analogs was proposed by copolymerizing the sulfonated unit and the glyco unit, ‘splitted’ from the sulfated saccharide building blocks of GAGs. The synthetic polymers can promote cell proliferation and neural differentiation of embryonic stem cells with the effects even better than those of heparin.