Nanoscale--Self-assembly of glutathione S-transferase into nanowires
writer:Zhang, Wei; Luo, Quan; Miao, Lu; et al.
keywords:Glutathione S-transferase, Nanowires, Self-assembly
source:期刊
Issue time:2012年
This study presents the Ni-ion-directed self-assembly of a C2-symmetric homodimeric enzyme into nanowires. A genetically introduced His-tag arm stretches out of the central structure of a C2-symmetric homodimer of glutathione S-transferase, which is used as a linker to recruit a second building block through interprotein metal coordination, forming self-assembled one-dimensional nanostructures with excellent enzymatic activity.