Composite nano-TiO₂with doping Fe³⁺Rand Agwas prepared, and furthermodified by 3-methacryloxypropyltrimethoxysilane.They were characterized by Zetasizer Nano ZS Particle and Zeta Potential Analyzer, X-ray diffraction, UV–Vis spectrophotometer, FT–IR spectra, and transmission electron microscopy. The modified composite nano-TiO₂ was applied to prepare multifunctional fluorocarbon coatings (FCC). Antibacterial activity of multifunctional FCC containing
modified composite nano-TiO₂ was investigated. Its photocatalytic antibacterial activity reached 92%. The influence of doping ingredients, amount of composite nano-TiO₂, different light houses, or surface modification was discussed. The surface of FCC cannot be easily smirched by oiliness, dust or water because of hydrophobic fluorosilicone emulsion. It would be an available modern interior building coating for its remarkable photocatalytic antibacterial property as well as self-cleaning function.